????

??? ? ?????????????????????????????????????

????????????????????50%70%

??2000???????????700??????????????20????

?????????????????????????

???????????????

???????????200????????????????????????
??,??BB??,????,?BB,???!

?21?????DS
??????????????????24?????21????????????????????????
???p???????????
???1/7001/900??20???
????????95%????????????????????20%?3580%?35
?????1%88%??3%??
??DS???????????????????DS???????????????1419?????2ml??
???????????????????????????????????????????????????????
?????????21???????21?????...

??21-?????????21????????????19?????????John Langdon Down


?
1866????????????Mongolism????mongolian idiocy???????????????????????

1959?????(Jerome LeJeune)???21???????????

1961????The Lancet???

1965?WHO??????



???????????660????????????????2024???1/149040?1/10649?1/11?????I?????80???35?3...