?????

?????????????????????????
????()???????????????? b` t????` ???????????. ?(??????)(???)?(SLE,????)???(?)????(??)????(?????)??? ??( AIDS)?

???B???????10,000??????????????BCR????B??BCR?????B????BCR???????BCRB????????B?????(????)

(?)B????

?B?????????????????(clone)????????????(memory cell)

???TH???M?MHC??????M????MHC??TH???M?MHC+????B?MHC??????TH???AgB???????

()?
????????????2000???????
??\"Y\"????????(FC)?(?)?????
()???
????...

??????^?????????Y????Y????????X/Y????????????Y?????????X??????????????????????????????????

???
1B??
2T??
3?
4??
??
1??
1?
2??IBD
3?????
2??
3?
4???

5AIDS

      ????????Lentiviruses??HIV-1HIV-2????100120nm????????RNA???reverse transcriptase?integrase?protease??????p17/18p24/25????gp120gp41???11-1gp120???gp41????
     
        HIV???CD4+T???????????CD4+T?????????
&nbs...