???

????????????????????????1??????????????????????????????????????????????
?????????????????????????????????????????????????????3??????????????????????????????

??????????????????
B???????????
???
???

???????
??
??
???
?

??????????????????????

?
1.?????????22??20?
2.??
?
1 ???????????????????????????????????????
2??????????2325????????????????????
3????????????????????????????????2029??035%20???076%???69 ??????18???26???20?????

(?)? ???????
1.??? ???????????????????????????
2.???? ????(placental sulfatase deficiency)????Ryan 1980?????16-OH-DHEAS????????????
3.?M ?????k?????????????
4.? ???????????
()
?????????????????????????
???5????????????36????????????????????????42?????????
1.?? ???????????????????
2.?? ??????????????...

????????????????????????????????2029??035%20???076%???69
    ??????18???26???20?????

1.?2.???????3.?????????4.
????????2000???5000
????????????????????