??????????

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? D ??????? 125 000 ?????????? D ??????????X?X??? PHEX ????????????????? 50%?????????????????????????????FGF23DMP1?????50%????l/3 ????????????X???D?????PHEXFGF23DMP1??????
?D
?D
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?D?????
?D...

????????06400mg,7?3600mg,3800mg,??10001200mg.,?D?I???,?,??,??,A??.

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????????????VitD400-1000U/d(10-25g/d)3?25-(OH)D??VitD??VitD?25-(OH)D??

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: 6(?3)??????????????????AKP???25-(OH)D ?X????????
: : <6?,???(??); > 6?,????????O?X???????AKP??25-(OH)D 1,25-(OH)2D .X?...

PTH??????????????? (PTH)?????????????????



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7.? ?????(?)??
8. ????????;?????Sudecks????)?
9. ??
10.???
11. ???????Mast-Cell?
12.? ??????

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55????????????????????????????????????????????????????l-a-??1.25-(OH)2-D3????1-a??????(PTH)???????1.25-(OH)2-D3??...