???????

???-?????20071?1
1. ????????
2. ???????N????????????
3. ??????Chagas?????
??????????????X??????
????????????????????????????(?)???????????????????????????X?????;?????
???X??,?X?????????????????,?,??????,???????,?315%??????,,?????,??,????,???,????????
?????????????,?????(pseudoachal...

??? ?????????????1%??????????nifedipine???????????????????
?? ????????????????????2/3?????????????????

???
???????--???????t???????????????????????????

???????????15-20???2???????????????~???????

?????10?1??????????????X???????
??? ?????????E?????(LES)?????1978Weiser????10mg?4???????????LES?????
?? ?????????????????????????????????510???5??60%80%?????????1%6%?
? ???Heller??????????????????????????80%85%???????????
??????Heller??????????94%????3%????????????????????S????
???????m???