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??????????????????????
??????????????????20:1???40??^
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????40%~80%????????????????????????????????????????????
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???????k???? ???????????90%????????????????????????????????????????
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????????????1/4??200X????B??PH8.0??100
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90%??????????????????17%~25%??
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?????????????>0.42mmol/L??????????????????????
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??????????????????????
?????????????T??????????????????<1g/kg/????>2000ml/????????????????????????????????????

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???CRF???
?(?)
    ?(GFR)8050ml/min(?CFR)?{(Scr)133177mol/L??????
?(?)
    ?(GFR) 5020ml/minScr186446mol/L)???????????????
(?)
    GFR 2010ml/minScr451707mol/L????????????????????
(????)
    GFR 10ml/minScr707mol/L

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???????????????????????????1.0151.030 ???????????????????????1.0100.003?
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1. 3??
(1)??????>171mol/L???????????ALT?????????;
(2)?????3?23????;
(3)????????????????1????q???
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6.??? ?????(2)??23????????28??
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35??(???)?
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?????????????chronic type??accellerated type???????????????????1%5%

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